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The sulfiredoxin-peroxiredoxin (Srx-Prx) axis in cell signal transduction and cancer development
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CBS selectively replenishes the GSH levels under cystine-restricted conditions Multiple critical enzymes are involved in the normal function of the TSS pathway, including CBS and CSE, which catalyze the first two steps of de novo cysteine generation, from homocysteine to cystathionine and then cysteine
Under the trial-product estimand (assuming participants stayed on treatment), the reduction was 22.7%
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