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Luminescence was measured on GloMax96 microplate reader (Promega, WI)
Although glutathione is found in virtually every cell of your body, its especially concentrated in your liver where it helps with detoxification
The expression of IDO1, TDO2, and other enzymes in the kynurenine pathway varies widely among different tumor types and even among patients with the same type of cancer ( While preclinical studies have demonstrated the potential of targeting the KP to overcome drug resistance, translating these findings into clinical practice will require carefully designed trials
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