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Among patients with type 2 diabetes, the risk of NAION was increased by 4.28 times, while in those using the drug for weight management, the risk surged by 7.64 times
To confirm the expression levels of MOTS-c in -cells, we performed immunofluorescence staining for insulin, MOTS-c and IL-1, a key cytokine associated with the senescence-associated secretory phenotype (SASP) 43
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161 However, these problems have not been shown to have a clear causal relationship with GLP-1RA in the general population, and there is a lack of data specific to the MASLD population, especially in individuals without co-existing T2DM
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