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This is because they have trouble absorbing B12 from food
This can sometimes make you feel tired
The titration schedule starts at 2 mg per week for 4 weeks, escalates to 4 mg for weeks 5 through 8, then to 8 mg for weeks 9 through 12, and reaches the 12 mg maintenance dose at week 13 (Jastreboff et al., NEJM 2023)
Staff are often unfamiliar with the product entirely, commonly confusing it with sterile water or saline flush
Optimization and Plateau Considerations (Weeks 12-16+): After 12-16 weeks of use, the rate of body composition change may slow as users approach their genetic set points or as the body adapts metabolically
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