In my practice and inside my Shift Your Gut Therapy program, I help people who are: on GLP-1 medications and suddenly dealing with constipation, bloating or reflux living with IBS or functional bowel disorders, now layered with GLP-1-related changes wanting to support their metabolic health and protect their long-term gut health We look at: your specific bowel pattern and symptom history your eating rhythm and food choices now (not just before the medication) hydration, stress, sleep and movement patterns evidence-informed tools to support motility and comfort GLP-1 medications can be a powerful tooland so can understanding and supporting your digestion while youre on them
Additionally, the benefits of GLP-1 RAs for treating diabetes as well as obesity and also expanded applications like cardiovascular disease management are paving the way for developing novel metabolic therapies
(2020) and, more recently, by The reasons why GLP-1, but not GIP, remains insulinotropic in T2DM are still unclear but may be related to the receptors differing signaling profiles (Yabe and Seino, 2011
As such, investments in oral GLP-1s may generate value well beyond a single indication, laying the groundwork for a new generation of orally delivered biologics
Ito W, et al