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mean age, 58 years), with 31 each in the combination therapy and semaglutide groups and 30 in the cagrilintide group
Studies involving approximately 900 participants consistently demonstrated fat loss without changes in IGF-1, preserved glucose homeostasis despite fat reduction, absence of anabolic tissue growth effects, and safety profile comparable to placebo
Their blood protein patterns also pointed toward healthier liver function and less activity in pathways associated with scarring and disease progression
optional extension to 16 weeks based on research protocol
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