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Revisiting proteasome inhibitors: molecular underpinnings of their development, mechanisms of resistance and strategies to overcome anti-cancer drug resistance

10.1016/j.nano.2020.102149 Nanomedicine 102 DesaiB

347 Olivia Majer and colleagues have elucidated that the late endosomal BLOC-1 (biogenesis of lysosomal organelles complex 1) related complex (BORC), in conjunction with the small guanosine triphosphatase (GTPase) ADP-ribosylation factor (ARF) like GTPase 8B (ARL8B), regulates intracellular TLR7 levels by modulating receptor turnover

Vitamin A and carotene values of institutionalised mentally retarded subjects with and without Downs syndrome