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In this study, we used population #pharmacokinetic #modelling to characterize the distribution of six key antituberculosis drugs across the cerebrospinal fluid and CNS tissues of rabbits with tuberculous meningitis
It remains a research compound, and its effects in humans have not been established through large-scale clinical trials
Interestingly, NAC exerts a GSH-supplementing effect in GSH-deficient cells, whereas this effect may be ineffective in GSH-enriched cells [101]
This results in increased production of desirable hormones (LH, GH), and decreased the production of undesirable ones (cortisol and somatostatin)
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![Oral Small-Molecule GLP-1 Receptor Agonists: Mechanistic Insights and Emerging Therapeutic Strategies[v1]](https://www.preprints.org/frontend/manuscript/7be468775bea75bf2036c55c34b8f0dc/download_pub/figure/graphic_abstract.jpg)
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