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A meta-analysis of 42,920 participants from five randomized trials demonstrated that GLP-1 RAs are associated with a significant reduction in the risk of the composite cardiovascular disease in patients with diabetes and established ASCVD [53]
doi: 10.1007/s12519-018-0198-7 75 HybyeCHildingAJacobssonHThornM
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In addition to GLP-1 and ATP, for example, GLUTag cells also secrete several other peptide hormones 36 including CCKa known stimulus of Ca 2+ -responses in ND ganglion neurones 37 as well as glutamate 38 , which has been reported to target NMDA receptors on the afferent vagus 39 and to underlie L-cell to nodose neuron signalling 40
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