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Targeted B12 supplementation may help manage symptoms of dysautonomia and peripheral neuropathy
Cardiovascular data on endpoints like MACE-3 or MACE-4 are presently not available yet, but an early meta-analysis demonstrated at least cardiovascular safety in patients with T2D treated with tirzepatide (78, 79)
Before initiating therapy, clinicians should assess baseline factors including HbA1c, weight, blood pressure, renal function, and cardiovascular history
The therapeutic mechanisms of established clinical drugs are being re-evaluated
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