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CI will be indicative of synergy, antagonism or additivity when CI is under, above or equal to 1, respectively [27]

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Depending on the severity and pattern of depressive episodes, different treatments are recommended, including psychological treatment and antidepressant medications (Shusharina et al., 2023), but a significant proportion of people who received treatment still fail to achieve remission (Mauskopf et al., 2009

10.1007/s12192-016-0726-0 45 GiulioniC.MauriziV.GalosiA

I mostly gave up alcohol for a couple of years, only having the odd drink here and there as the debilitating hangover just wasnt worth it