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In recent decades, researchers have focused on developing drugs that target proteostasis pathways, such as the ubiquitin-proteasome system (UPS), unfolded protein response (UPR), and heat shock response (HSR), to induce proteotoxic death in tumor cells [7, 8]
Data analysed by two-way repeated measures ANOVA to assess main effects of treatment ( b , c , f , g , i and j )
GEFs and GAPs: critical elements in the control of small G proteins
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