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Tirzepatide is eliminated via peptidase cleavage and renal filtration, while L-carnitine is absorbed in the small intestine and excreted unchanged in urine

[4] [6] The primary function of L-carnitine is to transport long-chain fatty acids into the mitochondriathe energy-producing structures within cellswhere they are oxidised to produce energy

Likewise, tirzepatide effects at the GLP-1R, like other specific GLP-1RAs, may improve endothelial function, suppress the renin-angiotensin system, and exert natriuretic effects