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Tirzepatide SC (Mounjaro/Zepbound): Dual GIP/GLP-1 agonism produces the greatest weight reduction among approved agents up to 2024% in non-diabetic patients (SURMOUNT-1)
There were hurt feelings probably from both of us. How GLP-1s can affect libido GLP-1s help regulate appetite and blood sugar by mimicking hormones released by the gut after eating but they can also affect the brain and body in unexpected ways
This fermentation, though less extensive than with other fibre types, can produce short-chain fatty acids (SCFAs) such as butyrate, propionate, and acetate, which may stimulate L-cells in the colon to secrete GLP-1
Some agents in this class (liraglutide, semaglutide, and dulaglutide) have demonstrated cardiovascular benefits in patients with established cardiovascular disease, while exenatide showed a neutral effect in cardiovascular outcome trials
