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IGF-1 is associated with muscle repair, cellular growth, and metabolic signaling

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norepinephrine increases both total peripheral resistance, as well as systolic and diastolic blood pressure Note : Compensatory vagal reflexes tend to overcome the direct positive chronotropic effects on the heart (since both branches of the ANS innervate the SA node), but do not eliminate the positive inotropic effects on the ventricle (which does not have significant vagal innervation)

Zeng H, Shen EH, Hohmann JG, Oh SW, Bernard A, Royall JJ et al (2012) Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures