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Primary endpoint in expanded populations and high-risk subgroups Semaglutide versus sitagliptin Among patients with obesity and type 2 diabetes at low, moderate or high cardiovascular risk in clinical practice, the 1-year risk of the composite endpoint of myocardial infarction or stroke was 1.5% (95% CI 1.4% to 1.6%) with semaglutide compared to 1.7% (95% CI 1.6% to 1.9%) with sitagliptin
Mechanism: Collagen peptides provide building blocks for type II collagen synthesis and signal chondrocytes to produce more collagen and proteoglycans in cartilage matrix
Patients might unknowingly use degraded medication, reducing treatment benefits
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The dietobesitybrain axis: metabolic, epigenetic, and DNA-repair pathways linking eating patterns to cognitive aging, with an AI-enabled translational perspective
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