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A notable 70.2% of SELECT participants were on beta-blockers, which can affect weight loss

Cells involved in repair (fibroblasts, endothelial cells, muscle cells) appear to respond through signaling changes that support migration, collagen organization, and local tissue rebuilding

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Research on the Mounjaro and retatrutide trials suggests this typically accounts for around a quarter of total weight loss, similar to whats observed with other forms of significant weight reduction

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