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First, gastrointestinal distress: tirzepatide's most common side effects are nausea (up to 31% of patients in SURPASS trials), vomiting, diarrhea, and decreased appetite
Some common Mounjaro side effects that may be likely when you start taking it include: feeling sick (nausea) being sick (vomiting) diarrhoea constipation stomach pain As your body gets used to Mounjaro, these side effects should become more manageable and go away completely
H.et al (2024)
Accessed April 2, 2026.
DOI: 10.1385/CT:4:3:287 45
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