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Meanwhile, a post-hoc analysis of the STEP 1 and STEP 4 trials showed that semaglutide 2.4 mg was associated with an approximately 60% reduction of the 10-years risk of T2D according to the Cardiometabolic Disease Staging (CMDS) calculator, regardless of patients baseline glycemic status 74
Participants applied the lotion twice daily for ten weeks, and results showed a significant reduction in skin melanin compared to a placebo
Subsequently, biodistribution studies of DSePA were carried out in a mice model, which indicated that DSePA was maximally absorbed in the lung tissues [90]
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