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GLP-1 agonists affect fetal weight, growth and skeletal ossification in animal studies, although liraglutide and exenatide do not cross the placenta
The incidence of severe hypoglycemia in pediatric patients with type 1 diabetes receiving TOUJEO as part of a multiple daily injection regimen was 6% at 26 weeks and the incidence of hypoglycemia accompanied by a self-monitored or plasma glucose value less than 54 mg/dL regardless of symptoms was 80.3%
PlexusDx compounded semaglutide injections are $189/mo month-to-month, or from $149/mo on the 6-month plan, making therapy accessible to patients who would otherwise be priced out
Key Takeaway: Retatrutide is moving quickly through trials, but approval timing is still uncertain until regulators review the full evidence
In dogs, it is most frequently recommended for heart disease
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