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Cureus 16 , e55004 (2024)
Adapted from: Ast J, Novak AN et al
As in women, most of the benefits likely come from improved metabolic health, not direct effects on reproductive hormones
The interaction of GLP-1 with the GLP-1R increases insulin secretion in response to glucose and decreases glucagon levels through increasing intracellular cyclic adenosine monophosphate (cAMP) [7]
The study authors did a commendable job bolstering the case that this was a good apples to apples comparison by first comparing only people getting new diabetes medication, then statistically controlling for a whole range of other sociodemographic factors (age, education, race/ethnicity, area-level income) and MANY baseline health characteristics and health behaviors
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