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Heat stress can preferentially induce germ-cell injury through ROS accumulation, DNA damage, mitochondrial dysfunction, and activation of caspase-dependent apoptotic pathways (Robinson et al., 2023)

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14 , e4 (2012)

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42 The FIGHT trial, which enrolled patients hospitalised for acute decompensated HFrEF, showed no improvement with liraglutide on the primary composite endpoint of death, HF rehospitalisation or change in N-terminal pro B-type natriuretic peptide levels