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10.1111/andr.12228 127 RaoM.MaS.HuS.LeiH.WuY.ZhouY.et al (2017)

These findings are supported by data from a recent RCT exploring the effect of the GLP-1R agonist exenatide on alcohol intake in patients with AUD (99)

Research on Combined Approaches A 2025 meta-analysis of 33 randomized controlled trials, involving 12,028 participants, revealed that adding lifestyle changes to GLP-1 therapy resulted in an additional 7.13 kg (15.7 lbs) of weight loss , a reduction in waist circumference by 5.74 cm , a drop in systolic blood pressure by 3.99 mmHg , and a decrease in fasting blood glucose by 6.51 mg/dL

Available from: [Last accessed on 2022 Apr 25] [Google Scholar] Patient-centered care for patients with depression or anxiety disorder: An integrative review

That translates to roughly 71 pounds from a 249-pound starting weight