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10.1177/0333102417702132 Cephalalgia 22 GhaemiA.SajadianA.KhodaieB.LotfiniaA

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Patients at Risk for Bleeding The elderly and patients with obesity are most affected by the increased bleeding risk when combining GLP-1R agonists with antithrombotic drugs such as aspirin, clopidogrel, or direct oral anticoagulants (DOACs)

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In wild-type mice, cagrilintide activates c-Fos-expressing neurons in the dorsal vagal complex (DVC), lateral parabrachial nucleus (LPBN), area postrema, and nucleus tractus solitarius brainstem regions critically involved in satiety signaling and suppression of food intake