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Children with PWS have an impairment of central nervous system networks, including hypothalamic dysfunctions, which involve both the hunger/satiety circuitry and the main endocrine axes, and are also associated with temperature instability, high pain threshold, and aberrant sleep cycle [25]
A follow-up investigation of outpatient material
The tissue was mounted in an Ussing chamber (EM-LVSYS-4 system with P2400 chambers and P2404 sliders, all from Physiologic Instruments, San Diego, CA, USA
SCF PROM1 was found to bind CYE-1, potentially targeting it for degradation (Mohammad et al., 2018)
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