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GLP-1RAs may also have effects on a transcriptional level via protein kinase A (PKA), phosphorylating cAMP-response element-binding protein (CREB) in the nuclear membrane to enhance preproinsulin transcription [28]
Aging Cell 15 , 416427 (2016)
Improvements in cardiometabolic markers including waist circumference, blood pressure, hs-CRP, and lipid parameters were also observed
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