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The challenge is not whether GHK-Cu has biological activity (that is well-established) but whether that activity can be delivered to tissues at concentrations and durations sufficient to produce clinical effects beyond the skin surface
Characteristics of PCD include low carnitine levels in the blood, reduced carnitine reserves within cells, and an increase in carnitine loss through the urine
Ann Surg 251(4):615619
But they are as unpleasant as they sound
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