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DeLoughery, T
Liquid formats gaining popularity: Liquid L-carnitine supplements are growing faster than capsule formats because of perceived faster absorption and ease of use
However, this review also critically evaluates alternative explanations for the translational gap, including limited central nervous system penetration, insufficient pharmacodynamic target engagement, a mismatch between the drugs metabolic mechanisms and the amyloid-driven pathology of established AD, and the inherent limitations of preclinical models
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