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Finally, GSH is also a cofactor for several antioxidant enzymes
Without binders present, a meaningful portion can be reabsorbed
Chondrocyte dedifferentiation was majorly characterized as the reduced expression of COL2 and ACAN and enhanced expression of type I collagen and versican ( COL2 expression, but not ACAN ( In addition to dedifferentiation, another consequence of in vitro expansion is replicative senescence, which also significantly influences chondrocyte function
Kwon DH, et al
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