Recent enzymatic analyses in lymphocytes showed that BD patients in the depressive phase had lower levels of mitochondrial complex II activity compared to those in the euthymic phase, with a significant negative correlation between the Hamilton Depression Rating Scale score and mitochondrial complex II activity [50], providing a strong link between reduced mitochondrial function and current bipolar depressive phase
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Peer review Peer review information Nature Reviews Rheumatology thanks Caroline Jefferies, Amir Sharabi and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
By 2030, the market is forecasted to reach USD 289.06 million , contributing USD 46.36 million during the first half of the decade