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However, the results suggested that AZT long-term exposure caused deletion of mitochondrial DNA and neuron death [48]
and even antioxidants like glucosamine
Published research has explored its role in promoting angiogenesis (new blood vessel formation), upregulating VEGF (vascular endothelial growth factor), stimulating fibroblast migration and collagen deposition, modulating nitric oxide pathways, and protecting the gastrointestinal lining
Clinical implications: This "oxidative-genetic" hypothesis explains why vitiligo frequently develops at places exposed to sunlight, chemicals, or trauma, all of which are powerful oxidative stressors