Research suggests glutathione may shift melanin synthesis toward pheomelanin, a lighter pigment type, instead of eumelanin, which produces darker tones
& Erkul, I
One study of 30 patients on nasal glutathione dosed at either 300mg or 600mg daily in three divided doses vs placebo over a three month period found significant improvement in UPDRS scores in the treatment arms over placebo while other measures of toxicity such as cell counts, liver enzymes, creatinine, blood urea nitrogen, and urinalysis were not significantly different between placebo and treatment groups
TB-500 also appears to be generally well-tolerated, but again, safety data derived from adequately powered clinical trials is lacking
Instead, our findings suggest genetically predicted l-carnitine could be linked to higher risk of CAD overall and in men, and heart failure overall