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The GIP component may affect incretin-based medications differently than GLP-1 alone

GH and IGF-1 influence brain health and neuroprotection

Glutathione in particular has very low oral bioavailability versus near-complete IV bioavailability

One is Virta Health, which advertises its nutrition-focused weight management program as a proven approach for deprescribing GLP-1s when clinically appropriate. A Virta-funded study assessed 154 people with Type 2 diabetes who stopped using GLP-1 medications but continued following Virtas program, concluding that their weight did not significantly increase after a year