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LOOH also participates in regulating oxidative stress-related signaling pathways, influencing apoptosis and antioxidant defense mechanisms [93], underscoring its critical role in cardiovascular diseases such as atherosclerosis and in neurodegenerative diseases, triggering tissue damage and pathological progression [93]
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DEGs were converted into corresponding probes using the Perl script and entered into CMap
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MD simulations were performed to understand the underlying mechanism of insulin aggregation and suggested few crucial residue mutations to impede the amyloid formation (90, 92, 96, 99)
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