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There are a couple of possible mechanisms for this

References Min T, Bain SC

Screening of the title and abstracts of the included studies by extracting the results and assessing the validity of the studies were performed independently by two authors (SR and OA) to determine whether they were eligible or not

v Liver Transplants & Acute Liver Failure Acetaminophen toxicity has replaced viral hepatitis as the most common cause of acute liver failure in the United States and is the second most common cause of liver transplants in the United States

doi: 10.1161/STROKEAHA.123.044568 111 ZobelEHRipaRSvon ScholtenBJRotbain CurovicVKjaerAHansenTWet al