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When bound to these receptors, the action of GLP-1 antagonist has the following effects: Stimulates the production of insulin Reduces glucagon production in the liver Signals to the brain a feeling of fullness Slows the rate of gastric emptying This results in: Better regulation of blood sugar levels Reduction of appetite Reduction of food intake Weight loss In other words, patients get full quickly, stay full longer, and rarely have food cravings or hunger
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