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We used BV-2 cells to assess the dynamic of mitochondrial membrane potential and RET status changes following MPTP treatment

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When this mechanism does not work endometrial cells implant, proliferate, and invade the pelvic peritoneum

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Animal As a senolytic, FOXO4-DRI carries mechanism-specific theoretical risks discussed in the senescence literature including disruption of beneficial senescence surveillance and off-target effects on stem-cell populations that share features with senescent cells and senolytic translation from mouse to human has a history of failures