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Zepbound and other tirzepatide formulations work primarily by reducing hunger and increasing fullness signals in the brain, but recent clinical observations hint at mood-related effects
The STEP 1 trial showed that responders who achieved 5% weight loss by week 20 went on to lose a mean of 18.2% at week 68 [7]
CDA-HFD animals were allocated to treatment groups without randomization
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