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Eapen, MD, cautions, No, you should never start semaglutide at a higher dose
Zepbound carries a boxed warning regarding thyroid C-cell tumors (based on rodent studies) and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2), and in those with serious hypersensitivity to tirzepatide
The study could not find any association between treatment with semaglutide or tirzepatide and risk of optic neuritis, papilledema, or optic atrophy, compared with all other antidiabetic medications
Additionally, semaglutide reduces inflammation, a common issue in metabolic disorders
Developed by Eli Lilly, this synthetic peptide consists of 39 amino acids and is engineered with a C20 fatty diacid modification, which extends its half-life and enables convenient once-weekly subcutaneous dosing
