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To investigate the effects of 2DG on metabolism and the inflammatory response within the CNS, we utilized two complementary models of LPS-induced neuroinflammation, delivering LPS either systemically through intraperitoneal (ip) injection or directly into the CNS via intracerebroventricular (icv) administration
The intrinsic level of ROS in the intracellular environment plays an important role in the maintenance of cellular homeostasis in vivo
It is a poorer fit, or warrants caution, in patients with known sulfur or sulfite sensitivity, in poorly controlled asthma, and in anyone whose expectations are anchored to unproven claims particularly cosmetic skin-lightening
It has been proposed that the surface of C 60, together with malonyl groups, contains electron-deficient regions capable of accommodating superoxide radical-promoting dismutation reactions
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