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The mechanisms involve IGF-1-mediated stimulation of cellular proliferation, enhanced protein synthesis, and activation of anti-inflammatory pathways

They are not FDA-approved and have not gone through the review process applied to brand-name drugs

Clients receiving a 2.4 mg dose of semaglutide weekly experienced an average weight reduction of approximately 14.9% over 68 weeks, significantly surpassing the results of those on placebo

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The most common side effects are gastrointestinal: nausea (30-44%), diarrhea (19-30%), constipation (10-24%), and occasional vomiting (9-24%)