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Interestingly, the same results were not observed in healthy age-matched mice, as 6 weeks of progressive ladder-climbing RT (3 climbs, progression from 50% to 100%MCL, 5 times per week) decreased lipid peroxidation in the cerebral cortex but increased lipid peroxidation in the hippocampus (Feter et al., 2019)

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The Asp-glutamate transporter SLC1A3 is closely associated with the effect of ETC inhibitors, and the SLC1A3 site is amplified in subclusters of non-glial epithelial tumors and thus against aspartic restriction