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Why Even Small Weight Loss Matters People who are overweight (BMI in the 25 to 30 range) drop less weight on GLP-1s than those with clinical obesity, losing just 5%-10% of their body weight on average versus 15%-20% for the obese cohort

GLP-2 receptor expression in excitatory and inhibitory enteric neurons and its role in mouse duodenum contractility

Most GLP-1 medications use very fine needles, often 30 or 32 gauge

Studies show that patients who discontinue semaglutide regain approximately 50% of their lost weight in the first year off treatment, and many regain more over time

AND IM ALSO A BELIEVER IN USING COMMON SENSE TO FIGHT WEIGHT LOSS, SOMETHING IVE LIVED WITH SINCE STANDING UP TO SAY THE PLEDGE OF ALLEGIANCE IN THE THIRD GRADE AND NOTICING MY PANTS WERE TIGHT