Homocysteine may inhibit thrombomodulin expression by altering the thiol redox-regulated intracellular transport, and may inhibit thrombomodulin activity by altering the disulfide-bondrich motif inside the protein, protein C activity (Lentz, 1997
If you are using IV glutathione, your provider will recommend a schedule based on your goals
Yes - same time on the same day at different sites is the standard pattern
All the differences still have statistical significance after controlling for age, sex, BMI, smoking, and drinking
After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency