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Five studies enrolled participants with MDD, 16,17,19,20,25 and four focused on dysthymic disorder (DSM-IV criteria)
Maximum doses of 10 mg often provide adequate efficacy with better tolerability than 15 mg in elderly populations
According to the pricing structure of the pan-Canadian Pharmaceutical Alliance, when two generic medications enter the market, they are at least 50 per cent cheaper than the brand name but companies can price them lower
However, its critical to consider the context
OTUs were assigned using a closed-reference OTU picking approach, which referenced picks against SILVA (NR132) database [35, 36] by using UCLUST algorithm [37] with 97% of sequence identity
