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"Are vitamin B-12 injections helpful for weight loss?"

When injected, B12 is more easily absorbed as it bypasses your gut and instead enters the bloodstream directly

Many people notice an improvement in energy and mental clarity within a few days of their first injection

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Importantly, in the same paper the anti-obesity efficacy experiment in diet-induced obese mice was carried out by systemic administration of the inhibitor the researchers did not report an oral-gavage efficacy arm