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As for cons: Repeated injections in the same area can cause lipohypertrophy , a condition in which the fat under the skin thickens or hardens
DMH, dorsomedial hypothalamic nucleus
Judaki A, Rahmani A, Feizi J, Asadollahi K, Hafezi Ahmadi MR (2017) Curcumin in combination with triple therapy regimes ameliorates oxidative stress and histopathologic changes in chronic gastritis-associated Helicobacter pylori infection
2012 Jun;153(2):255-8
It fails on the fourth pillar because meal replacement dependency is inherently unsustainable for most people
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