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It's one of the most widely prescribed weight-loss and diabetes medications on the market

Semaglutide, marketed under brand names including Ozempic, Wegovy, and Rybelsus, is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management and chronic weight management

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Bloating and increased gas are also reported during the first few weeks

The decision to use this combination as initial therapy should be individualized and should be shaped by considerations such as baseline blood pressure, the target goal and the incremental likelihood of achieving goal with a combination compared to monotherapy