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Many patients report that anticipation of the injection causes more anxiety than the injection itself, a phenomenon well-documented in medication compliance research

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12), which may be associated with the greater dynamics within the bundle, given the bound peptide bridges these two domains and stabilises their motions relative to one another

The VO 2 max was assessed as the maximal oxygen uptake during incremental physical exertion on an ergometer, lean body mass was estimated through bioelectric impedance analysis and the HPA based on the self-report that addressed the following main components: physical activity during work, physical activity during leisure time and sports during leisure time 74