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the expression level of the above proteins was decreased after melatonin was applied, and mitochondria biosynthesis was increased and apoptosis was decreased, which has some therapeutic value for diabetic macular edema (DME) with certain therapeutic value [164].In addition, in HG-induced mouse retinal ganglion cells (RGC-5) and HG/HFD-induced SD rat models, liraglutide was found to inhibit the PINK1/Parkin pathway to suppress mitophagy, which exerted a preventive effect on DR [165]

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Gutmann, DH

The diet, which was introduced to patients with type 2 diabetes, was shown to improve glycemic control

While microglia are central mediators of neuroinflammation, the requirement for neuronal GLP-1R activation suggests coordination between neurons, glial cells, and vascular components